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OHSU # 2917 — Sensorless adaptive optics (AO) control method for OCT/OCT-angiography retinal imaging

Summary

Researchers have developed an improved method of adaptive optics for OCT/OCT-angiography retinal scanning that is sensorless and allows for optical aberrations correction without considerably increasing scan times.

Technology Overview

Adaptive optics OCT (AO-OCT) allows for high lateral resolution imaging of the retinal tissue and blood flow by compensating for ocular aberrations. However, translation of AO-OCT from the bench to clinic has been challenged by a number of factors, including large instrument footprint, high cost, narrow field of view (FOV), and long scan times. OHSU researchers have developed a sensorless adaptive optics OCT/OCT-A technique, using hill-climbing and adaptive step methods, with the following advantages:

  • Low-cost, maintenance-free adaptive optics;
  • Fast and reliable aberration correction for specific retinal layer of interests;
  • Robustness to ocular motion artifacts; and
  • Reduction in the duration and number of volumetric scans needed for aberration characterization.

This method could overcome the previous limitations of adaptive optics in OCT/OCT-A retinal imaging, making it easier for clinical adoption of this imaging modality within OCT instruments. 

Publication

Camino et al., "Depth-resolved optimization of a real-time sensorless adaptive optics optical coherence tomography" Optics Letters 45(2020):2612-2615. Link

Licensing Opportunity

This technology is available for licensing.

 

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Patents

Filed United States
Published United States US 2022/0299753 A1

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