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OHSU # 2413 — A therapeutic approach to minimize residual disease and relapse in cancer

Technology Overview

OHSU researchers have identified a novel treatment method which, when used in combination with first-line cancer therapies, has the potential to minimize residual disease, the primary cause of relapse in all cancers.  The method leverages existing drugs that inhibit a metabolic target molecule not previously understood to be involved in autophagy, a biological mechanism that supports tumor cell survival.  Inhibition of this target, combined with standard therapy, can be used to treat cancers more effectively.

Licensing Opportunity

This technology is available for exclusive licensing and/or collaborative co-development. 

Inventors:

• George Thomas
• Hui-wen Lue
• Jennifer Podolak
• Kevin Kolahi

Patents

Categories:

• Therapeutics - Cancer

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