Categories  |  Inventors

Technology Overview

OHSU # 2936 — DailyDose decision support smart phone app to improve glycemic control in type 1 diabetes (T1D)

Summary
A smart phone application and graphical user interface, which provides real-time dosing advice and weekly insulin dose adjustments to improve glucose management in patients with type 1 diabetes using daily insulin injections.

Technology Overview
Close to 1.5 million people in the US have type 1 diabetes and many have difficulty managing their glucose effectively, particularly those without access to automated insulin pumps.  These patients must attempt to accurately dose themselves multiple times a day with insulin injections to achieve stable glucose levels.  Factors such as meal size and exercise can affect insulin sensitivity and make it difficult to determine insulin dosage.

DailyDose is the only smart phone application designed to help patients with type 1 diabetes manage their glucose by providing weekly insulin recommendations, and has been shown in preliminary studies in human patients to improve glycemic control.  Features of the application and graphical user interface include:

  • A bolus calculator for calculating insulin prior to meals (meal boluses) or when glucose is too high (correction boluses).
  • Weekly recommendations for changes in insulin dosing or behavior, based on the “recommender engine” artificial intelligence (AI) algorithm.
  • An alert system to notify users of predicted incidents of hypoglycemia, including nocturnal hypoglycemia, based on novel AI algorithms.
  • An ability to view current glucose levels as well as personalized insulin profiles, based on users entered carbohydrate consumption and correction factors.
  • An insight feature that empowers users by allowing them to see how past adjustments to their insulin dosing and behavior have impacted their glycemic control.
  • On-demand exercise advice.

This application is approved by the FDA through an investigational device exemption for use in a clinical study, the first of which is currently starting at OHSU.

Publication
Castle JR, et al., Assessment of a Decision Support System for Adults with Type 1 Diabetes on Multiple Daily Insulin Injections. Diabetes Technol Ther. 2022 Dec;24(12):892-897. Link

 

Licensing Opportunity
This technology is available for licensing.

 

Inventors:

Categories: