Categories  |  Inventors

Technology Overview

OHSU # 1222 — Bacterial artificial chromosome (BAC) clone containing the genome of human cytomegalovirus (HCMV) TR strain

Technology Overview
The TR BAC was prepared from the TR clinical HCMV isolate. This virus is resistant to ganciclovir and cidofovir and lacks UL97 codons 591-594. The BAC clone was generated by substituting BAC DNA for the US2-US5 region of the TR genome. The TR strain infects almost any diploid endothelial or epithelial cell as well as macrophages.  This strain is useful for studies on HCMV including genetic studies.

Murphy E, et al., Coding potential of laboratory and clinical strains of human cytomegalovirus. Proc Natl Acad Sci U S A. 2003 Dec 9;100(25):14976-81. Link

Licensing Opportunity
This technology is available for non-exclusive licensing as a research tool.



Agreement Type Price
NE Biological Materials License $10000.00