Relationship between HLA B27, disease status and the human microbiome
The purpose of this study is to learn more about the relationship between the microbes which naturally reside in the gut and other organs of the body and diseases that are associated with a gene called HLA B27. We are also investigating whether the preparation done before colonoscopy procedures changes the bacteria that live in the gut, and how these bacteria vary in different parts of the large intestine.
Ankylosing Spondylitis (AS)
Inflammatory Bowel Disease
-At least 18 years of age
-Scheduled for a routine colonoscopy
-Willing and able to give consent, provide samples and complete study paperwork
-No history of bowel or intestine surgery
-No diagnosis or history of colon cancer
-Have not taken any antibiotics in the past 3 months
Healthy Volunteers Needed
Duration of Participation
Your primary involvement will last only on the day of your colonoscopy. All subjects will be asked to obtain a stool sample at home prior to your colonoscopy prep. Subjects who agree to an optional second stool sample will do so within 2-3 weeks after the day of your colonoscopy.
$10 clincard upon completion of study specimen(s). For most subjects this will be a one time event. Some subjects will have the opportunity to provide specimen(s) more than once.