A Phase 1a/1b Open-Label Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of PY159 as a Single Agent and In Combination with Pembrolizumab in Subjects with Advanced Solid Tumors
The purpose of this study is to find out if the investigational drug called PY159 is safe in people with cancers that have a specific mutation and what effects it has on that cancer. PY159 is being looked at as a single drug and also in combination with the drug pembrolizumab.
Male and Female participants of 18 years of age and older.
Diagnosed with advanced or metastatic cancer
18 - 99
Healthy Volunteers Needed
Duration of Participation
How long you participate in this study depends on side effects you may have to the study drug. It also depends on how your cancer might respond to the study drug.
If your cancer improves or stays the same and you do not have serious side effects from the study drug, you may remain in the study as long as your study doctor feels you may benefit. However, you are free to stop taking part in this study at any time and for any reason.
Knight Clinical Trials Information Line
Pionyr Immunotherapeutics, Inc.