Serial Measurements of Molecular and Architectural Responses to Therapy

Principal Investigator

Raymond Bergan

Study Purpose

The purpose of this study to test samples from a patient's cancer can be used to find combinations of drugs that best combat the kind of cancer the patient has. Another purpose of this study is to test patients' cancer cells to understand why cancer drugs stop working.
In this study, we will take blood and tissue sample from patients and test them to determine your complete DNA sequence, called whole genome sequencing. We will do other kinds of genetic testing, also, to understand as much as we can about the kind of cancer you have.

Medical Condition(s)

Metastatic Breast Cancer, Metastatic Pancreatic Cancer, Metastatic Prostate Cancer, Acute Myeloid Leukemia

Eligibility Criteria

Confirmed diagnosis of either prostate cancer, breast cancer, pancreatic cancer that has spread to other organs or acute myeloid leukemia.

Age Range

21 - 99

Healthy Volunteers Needed


Duration of Participation

Participant’s investigational treatment may last for 6 cycles or 6 months of investigational therapy. Participants will be followed for 12 months after their last treatment.

Minors Included



Swapnil Parmar,, 503-494-9642


OHSU Knight Cancer Institute

Recruitment End


Compensation Provided


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